Last edited by JoJot
Wednesday, August 5, 2020 | History

4 edition of Prediction of percutaneous penetration found in the catalog.

Prediction of percutaneous penetration

methods, measurements, modelling : proceedings of the conference held in April, 1989, 1991

  • 16 Want to read
  • 33 Currently reading

Published by IBC Technical Services Ltd in London .
Written in English

    Subjects:
  • Chemotherapy -- Congresses,
  • Injections, Hypodermic -- Congresses,
  • Medicine -- Congresses,
  • Skin absorption -- Congresses

  • Edition Notes

    Includes bibliographical references.

    Statementedited by R. C. Scott, R.H. Guy, J. Hadgraft.
    ContributionsGuy, Richard H., 1954-, Hadgraft, Jonathan, 1950-, Scott, R. C.
    Classifications
    LC ClassificationsRM169 .P74 1989
    The Physical Object
    Paginationv.
    ID Numbers
    Open LibraryOL20381859M
    ISBN 101852711175, 1852711876

      The book features contributions from over 40 top scientists and covers topics such as PBPK modeling, cytochrome P metabolism in skin, percutaneous absorption, adverse effects, new skin models, and the role of epidemiology in assessing the hazards of by: Prediction of percutaneous penetration methods, measurements, modelling: proceedings of the conference held in April, by R. C. Scott, Jonathan Hadgraft, Richard H. Guy Hardcover, Pages, Published by Hyperion Books ISBN , ISBN:

    The prediction of transdermal absorption for arbitrary penetrant structures has several important applications in the pharmaceutical industry. We propose a new data-driven, predictive model for skin permeability coefficients kp based on an ensemble model using k-nearest-neighbor models and ridge regression. The model was trained and validated with a newly assembled data set containing Cited by:   Percutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement: Drug Manipulation Strategies and Vehicle Effects - Ebook written by Nina Dragicevic, Howard I. Maibach. Read this book using Google Play Books app on your PC, android, iOS devices. Download for offline reading, highlight, bookmark or take notes while you read Percutaneous Penetration Enhancers .

    Percutaneous absorption of a lipophilic surfactant, dodecyl decaethoxylate, can be predicted using in vitro models. In vivo, dermal penetration of dodecyl decaethoxylate was found to be % in 48 h. All of the absorbed dodecyl decaethoxylate in the rat was metabolised and excreted in expired air as carbon dioxide, or in the urine and by: 8. Prediction of percutaneous penetration: methods, measurements, modelling: proceedings of the conference held in April


Share this book
You might also like
Moriah

Moriah

Current Issues in Cancer

Current Issues in Cancer

Left bank

Left bank

The Pied Piper of Hamelin

The Pied Piper of Hamelin

The United States, Britain, and appeasement, 1936-1939

The United States, Britain, and appeasement, 1936-1939

Bibliography of reading interests and habits, 1930-1936

Bibliography of reading interests and habits, 1930-1936

Reptiles and amphibians in captivity

Reptiles and amphibians in captivity

Review of the scientific basis of the Environmental Protection Agencys carcinogenic risk assessment on formaldehyde

Review of the scientific basis of the Environmental Protection Agencys carcinogenic risk assessment on formaldehyde

Symposium.

Symposium.

State aviation laws

State aviation laws

An Æthiopian historie, written in Greeke by Heliodorus, no lesse wittie then pleasaunt: Englished by Thomas Vnderdowne, & newly corrected and augmented with diuers and sundry newe additions by the said authour. Whereunto is also annexed the argument of euery booke in the beginning of the same, for the better vnderstanding of the storie

An Æthiopian historie, written in Greeke by Heliodorus, no lesse wittie then pleasaunt: Englished by Thomas Vnderdowne, & newly corrected and augmented with diuers and sundry newe additions by the said authour. Whereunto is also annexed the argument of euery booke in the beginning of the same, for the better vnderstanding of the storie

Summer spots and stains

Summer spots and stains

The drunkard kungfu & its application

The drunkard kungfu & its application

The concise Russian-English chemical glossary

The concise Russian-English chemical glossary

You can decoupage the plain and uglies around your house

You can decoupage the plain and uglies around your house

The official patients sourcebook on adult non-Hodgkins lymphoma

The official patients sourcebook on adult non-Hodgkins lymphoma

To the representatives of the people of the state of New-York, in Senate and Assembly convened.

To the representatives of the people of the state of New-York, in Senate and Assembly convened.

Haystack-Westford survey

Haystack-Westford survey

Banks and banknotes of Exeter, 1769-1906

Banks and banknotes of Exeter, 1769-1906

Prediction of percutaneous penetration Download PDF EPUB FB2

Prediction of Percutaneous Penetration: v. 1: Methods, Measurements, Modelling Paperback See all formats and editions Hide other formats and editions PriceFormat: Paperback. Prediction of Percutaneous Penetration Methods, Measurements, Modelling VOLUME 2 Proceedings of the conference held in April, Edited by R C Scott, R H Guy, J Hadgraft and H E Bodde Associate Editor Prediction of percutaneous penetration book M Tittensor.

A method for the prediction of in vivo blood levels during application of matrix-type and membrane-controlled-type transdermal File Size: 1MB. Full Description: "Percutaneous Penetration Enhancers in a mini-series format comprising five volumes, represents the most comprehensive reference on enhancement methods – both well established and recently introduced – in the field of dermal/transdermal drug delivery.

In detail the broad range of both chemical and physical methods used to enhance the skin delivery of drugs is described. SR-FTIR is a relevant analytical tool for studying and predicting percutaneous penetration of exogenous molecules. This study brings a new approach in mapping the prediction of exogenous molecules cutaneous distribution profiles regardless of their Log Pow or MW.

This requires setting up and following a very detailed operating by: 1. This book is a comprehensive reference on the methods available for the enhancement of percutaneous penetration.

It examines a broad scope of chemical enhancers and various physical methods of enhancement. The range of chemicals discussed in this volume is.

Thoroughly updated, this second edition is the most comprehensive reference on the methods available for the enhancement of percutaneous penetration. The book examines a broad scope of chemical enhancers and various physical methods of enhancement.

The range of chemicals discussed is, arguably, unsurpassed anywhere in the literature. "The book is an ideal and practical reference in Percutaneous Penetration Enhancers designed for researchers, students, biomedical and pharmaceutical scientists." —International Journal of Biological Macromolecules, September "Overall, I thought the book was a very well put together review of the field of percutaneous enhancers.

The validity of in vitro and in vivo methods for the prediction of percutaneous penetration in humans was assessed using the fungicide ortho-phenylphenol (OPP) (log Po/wMWsolubility in water g/L).In vivo studies were performed in rats and human volunteers, applying the test compound to the dorsal skin and the volar aspect of the forearm, by: Peck CC, Shah VP.

FDA requirements for approval of transdermal drug delivery systems. Scott RC, Guy RH, Hargraft J, eds. Proceedings of “Prediction of Percutaneous Penetration —Methods, Measurements, Modeling, “ Oxford: IBC Technical Services; – Google ScholarAuthor: Vinod P.

Shah, Thomas M. Ludden, Shrikant V. Dighe, Jerome P. Skelly, Roger L. Williams. Percutaneous penetration enhancers I edited by Eric W.

Smith, Howard I. Maibach. Includes bibliographical references and index. ISBN I. Transdermal medication. Skin absorption. Smith, Eric W. Maibach, Howard I. RMIP 'dc20 CIPFile Size: KB. The specific aims of the project were: (1) to derive, from a comprehensive database of the percutaneous absorption/penetration literature predictive ("structure-activity") algorithms to calculate.

Percutaneous absorption of a lipophilic surfactant, dodecyl decaethoxylate, can be predicted using in vitro models. In vivo, dermal penetration of dodecyl decaethoxylate was found to be % in 48h. All of the absorbed dodecyl decaethoxylate in the rat was metabolised and excreted in expired air as carbon dioxide, or in the urine and by: 8.

Prediction of the percutaneous penetration of ultra‐violet filters used in sunscreen formulations. A.C. WATKINSON. Corresponding Author. An‐eX, Redwood Building, King Edward VII Avenue, Cardiff CF1 3XF, UK *To whom correspondence should be for more papers by this by: Thoroughly updated, this second edition is the most comprehensive reference on the methods available for the enhancement of percutaneous penetration.

The book examines a broad scope of chemical enhancers and various physical methods of enhancement. The range of chemicals discussed is, arguably, unsurpassed anywhere in the literature.5/5(1).

Percutaneous Penetration Enhancers in a mini-series format comprising five volumes, represents the most comprehensive reference on enhancement methods – both well established and recently.

Try the new Google Books. Check out the new look and enjoy easier access to your favorite features. Try it now. No thanks. Try the new Google Books Get print book. No eBook available Prediction of Percutaneous Penetration: Methods, MeasurementsVolume 2 R.

Scott Snippet view - Synchronous Generators. Percutaneous Penetration Enhancers in a mini-series format comprising five volumes, represents the most comprehensive reference on enhancement methods – both well established and recently introduced – in the field of dermal/transdermal drug delivery.

In detail the broad range of both chemical and. Try the new Google Books Get print book. No eBook available membrane Menczel metabolism metabolites minoxidil molecules nitroglycerin occlusion ointment parathion partition coefficient percutaneous absorption percutaneous penetration permeability coefficients permeability constant permeation Pharm Prediction of Percutaneous Penetration.

Capt A, Luzy AP, Esdaile D, Blanck O. Comparison of the human skin grafted onto nude mouse model with in vivo and in vitro models in the prediction of percutaneous penetration of three lipophilic pesticides.

Regul Toxicol Pharmacol. ;47(3)–Cited by: Prediction of Percutaneous Penetration: Methods, Measure- ments, Modelling. Proceedings of the conference held in April, Edited by R.C. Scott, R.H. Guy, and J. Hadgraft, IBC Tech- nical Services Ltd., London, ( pp, £) This paper back book contains vignettes of current topics in phar.

While previous algorithms for predicting the skin absorption of permeants was based on in vitro data, the present article proposes a quantitative structure-activity relationship (QSAR) model based on in vivo human data.

Here, a set of human in vivo data is described that provides entry into predicting the penetration of cosmetic ingredients.Penetration enhancement science and methodology have changed and developed dramatically in every aspect of dermatology since the publication of the first edition of Percutaneous Penetration ghly updated, this second edition is the most comprehensive reference on the existing and experimental methods available in the field.Percutaneous Drug Penetration TRANSEPIDERMAL TRANSECCRINE I Fig.

ration showing the possible routes for percutaneous tly it is believed that a transepidermal route through the seams between the “cells” of the stratum corneum is the principal pathway for most drugs.